Some end users mash their capsules up right into a powder and split this into 4 equal portions. The powder can then be encapsulated or blended into a strong smoothie in the morning.
Medications.com Cell Apps The simplest way to lookup drug information and facts, identify supplements, Examine interactions and arrange your individual particular medication documents. Readily available for Android and iOS gadgets.
ketoconazole will raise the stage or outcome of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
To give you quite possibly the most related and handy information and facts, and realize which data is useful, we may well Merge your e-mail and website utilization info with other data We have now about you. Should you be a Mayo Clinic patient, this could include things like protected wellbeing information and facts.
nevirapine will minimize the extent or impact of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Applying this medicine with any of the next medicines is just not advisable. Your health practitioner may well come to a decision not to treat you read more with this medication or change several of the other medicines you're taking.
Metabolism: Modafinil undergoes hepatic metabolism by way of numerous pathways, including CYP3A4. 80% of the dose is recovered from the urine in the form of metabolites.
Dose changes of these prescription drugs as well as other medications that happen to be substrates for CYP2C19 may be essential if modafinil is coadministered
Modafinil and armodafinil had been examined as being a complement to antipsychotic medications in the procedure of schizophrenia. They confirmed no impact on optimistic indicators or cognitive performance.[243][244] A 2015 meta-Evaluation uncovered that modafinil and armodafinil may well marginally minimize unfavorable symptoms in those with acute schizophrenia, however they do not appear handy for individuals with the situation that are stable, with high detrimental symptom scores.
enzalutamide will lower the extent or outcome of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Hazard of skin reactions (eg SJS, poisonous necrolysis, and drug rash with eosinophilia and systemic signs); discontinue if rash or other hypersensitivity reactions take place
Acquire this medication only as directed by your doctor. Will not get more of it, will not get it additional usually, and don't acquire it for a longer time than your doctor ordered. If too much is taken, it may come to be routine-forming.
rifampin will lower the extent or effect of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unfamiliar.
Provigil hasn't been sufficiently researched in pregnant Women of all ages and it can be mysterious if it is excreted in breast milk. Consult your health care provider in advance of breastfeeding. Added Details